The Science Behind Erox
Erox is a functional fragrance containing two patented human pheromones and a new, patent-pending, organic pheromone-like compound derived from sea coral. Combined, these three ingredients create a very social and receptive mood in both the wearer and his or her audience. There is evidence from several independent research groups supporting that human pheromones upon binding to nasal chemosensory receptors can modulate brain functions and induce measurable physiological and behavioral changes (Monti L and Grosser Bl. 1991; Monti L et al, 1994, 1998, Monti and Winegar, 2002; Sobel N et all 1999 Grosser Bl et al, 2001, Jacob S and McClintock M 2002). The three active ingredients in Erox are Androstadienone (ADO), Estratetraenol (ETE), and Muricin Aglycone (ER303). ADO and ETE have been proven to cause gender specific responses with the primary result being increased feelings of confidence and well being. ER303 has been proven to increase arousal, excitement, sensuality, and social warmth in men and women. Additionally ER303 has been shown to have physiological effects that are similar to those found in a state of arousal. Most notably, these effects include increased cortical theta wave activity as measured by EEG.
About Muricin Aglycone (ER303) pregna-5, 20-dien-3-ol
Muricin Aglycone occurs naturally in marine corals but is synthesized (ER303) for Erox. Nanomol quantities of ER303 can activate human nasal chemosensory receptors. Erox is the only product on the market that contains Muricin Aglycone.
In a scientific study conducted through the University of Utah, Department of Psychiatry, University Neuropsychiatric Institute (Study Date: 10/05-6/06), significant effects of exposure to 12 ng ER303 were observed in both gender groups for the following:
- The physiologic effects of ER303 are decreased eye blinking, increased electrodermal activity, increased electromyogram activity, and increased theta frequency band of the EEG.
- The behavioral effects are increased social warmth, increased sensuality, increased well being and increased arousal and excitement.
The study compared the the effects of a placebo to the active substance to the nasal passages over a period of 20 minutes. In total 76 subjects complied with all the admission criteria stated in the research protocol and were admitted to the study. The results of the study are being finalized for submission in a peer review journal. In addition, the scientists who conducted this research have published on other compounds contained in Erox before. (http://www.ncbi.nlm.nih.gov/pubmed/10737699) The key difference between this study and previous ones is that Muricin Aglycone is odorless unlike most pheromone type compounds. This makes it easier to provide a placebo control since there is no odor to mask.
For more information please read this study: Physiological and psychological effects of ER303 in men and women
Patent Number: http://www.freepatentsonline.com/y2009/0075964.html
About Androstadienone (ADO) androsta-4,16,-dien-3-one
ADO is a chemical compound that has been described as having strong pheromone-like activities in humans. (Wyart C, Webster WW, Chen JH, Wilson SR, McClary A, Khan RM, Sobel N 2007). MRI studies have demonstrated that ADO applied intranasally activates basal forebrain structures, (Sobel N. et al, 1999; Savic I. et al 2000). Additionally, ADO has subtle effects on attention and the ameliorative effects on self-reported attentiveness have been replicated in scientific studies. (Hummer TA, McClintock MK 2009).
Researchers at the University of Chicago have found for the first time that airborne androstadienone, has a measurable impact on brain metabolism, according to a report released July 25, 2001. Read More
An independent study conducted by researchers at the University of California, Berkeley, and was published in the journal, Psychoneuroendocrinology, involved involved 4,16-androstadien-3-one (androstadienone). The study, conducted by members of the Neuroscience Institute and Department of Psychology at the University of California, Berkeley, measured the effects of sniffing different concentrations of the compound in the autonomic nervous system function and mood. Simply stated, higher concentrations of this compound increased positive mood and decreased negative mood in women tested. Read More
About Estratetraenol (ETE) estra-1,3,5(10),16-tetraen-3-ol
ETE is is a chemical compound produced by women that has been described as having pheromone-like activities in primates, including humans. It is derivative of the sex hormone, estradiol. (Savic, I; Berglund, H; Gulyas, B; Roland, P, 2001; Berglund, H; Lindström, P; Dhejne-Helmy, C; Savic, I, 2008; Berglund, H; Lindström, P; Savic, I, 2006)
In a 2005 study conducted by the Department of psychology, Uppsala university, University of Lusofona and McGill University, tested whether the mood of heterosexual men is affected by exposure of a putative female pheromone, estratetraenol. The results were that exposure to estratetraenol compared to a perceptually identical control substance enhanced positive mood. Participants were 80 males with a mean age of 24.4. A previous study showed that women’s mood was enhanced positively as a function of exposure to a subthreshold concentration of a putatively male pheromone, androstadienone (Lundstrom & Olsson, 2005).
This experiment is supported by the findings from Jacob and McClintock (2000) in that estratetraenol affected the mood of men. The results of this test further support the notion that subthreshold exposure to endogenous substances can affect mood. In particular, estratetraenol, affected the mood in men. The results are in line with the idea that human pheromones modulate psychological or physiological processes.
- “A Gene for Romance? So It Seems (Ask the Vole)” Washington PostBy NICHOLAS WADE Published: July 19, 2005
- “In Lobster Courtship, Traits Like Humans” New York TimesBy CORNELIA DEAN Published: August 9, 2005
- Bensafi, M., Brown, W.M., Khan, R., Levenson, B., Sobel, N., 2004. Sniffing human sex-steroid derived compounds modulates mood, memory and autonomic nervous system function in specific behavioral contexts. Behav. Brain Res. 152 (1), 11–22.
- Jacob, S., McClintock, M.K., 2000. Psychological state and mood effects of steroidal chemosignals in women and men. Horm. Behav. 37 (1), 57–78.
- Monti-Bloch, L., Grosser, B.I., 1991. Effect of putative pheromones on the electrical activity of the human vomeronasal organ and olfactory epithelium. J. Steroid Biochem. Mol. Biol. 39 (4B), 573–582.